The City of Destruction in Bunyan's "The Pilgrim's Progress" is no different than any other city or place in the 17th-century. It was a placed filled with worldly people and worldly cares - people who were not awakened to their sin, their need for grace, and the impending judgement. The city did not seem inherently evil, but it was filled with those who did not see their need for God.
Bunyan took the name for the city from Isaiah 19:18:
"In that day five cities in Egypt will speak the language of Canaan and swear allegiance to the LORD Almighty. One of them will be called the City of Destruction."
After reading a book (a symbol for the Bible),"The Pilgrim's Progress'" main character, Christian, awakens to the disastrous future of his city and cries out:
"I am for certain informed, that this our City will be burned with fire from Heaven; in which fearful overthrow, both myself, with thee my wife, and you my sweet babes, shall miserably come to ruin, except (the which yet I see not) some Way of escape may be found, whereby we may by delivered."
When Christian starts out on his journey to find deliverance from a future filled with destruction, his neighbors mock him and bid him to forget about his burden and to enjoy life. Worldly Wiseman, a resident of the City of Destruction, tells Christian that leaving the city and its way of life and going another is the most "dangerous and troublesome way in the world."